The pc12 cell as model for neurosecretion
Webb19 mars 2003 · Lixia Liu, Haini Liao, Anna Castle, Jie Zhang, James Casanova, Gabor Szabo, David Castle, SCAMP2 Interacts with Arf6 and Phospholipase D1 and Links Their … Webb1 sep. 2007 · The catecholamine-secreting PC12 cell line derived from the rat adrenal medulla has long been considered a model system for neurosecretion and neuronal …
The pc12 cell as model for neurosecretion
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WebbPC-12 cells have been widely used as a neuronal line study model in many biosensing devices, mainly due to the neurogenic characteristics acquired after differentiation, such as high level of secreted neurotransmitter, neuron morphology characterized by neurite outgrowth, and expression of ion and neurotransmitter receptors. WebbATP-induced inward currents were measured in mock-, wild-type or mutant (C90S)-UCH L1-transfected PC12 cells under the conventional whole-cell patch clamp configuration. The amplitude of ATP-induced currents was significantly greater in both wild-type and C90S UCH L1-transfected cells, suggesting that hydrolase activity was not involved but …
WebbThe PC12 cell line has been used to get more information about diseases of the brain. It has been used in research of hypoxia, where acute hypoxia induces exocytosis and … Webb25 sep. 2024 · To analyze a role of ERK1/2 in DA release we used differentiated PC12 cells. These cells have strong similarity in the synaptic machinery with neurons in the peripheral and central nervous systems that positioned PC12 cells as a perfect model for studding of neurosecretion [26, 27].
Webb11 okt. 2013 · (A) PC12 cells were treated with LPS, culture medium of BV-2 only, or culture medium of BV-2 cocultivated with1 mg/ml LPS. Then, cell viability was assessed by MTT assay after 18 h. (B) Effects of exposure of PC12 cells to resveratrol, nicotinamide for 24 h. Then, cell viability was assessed by MTT assay. Webb1 feb. 2008 · The PC12 cell as model for neurosecretion The PC12 cell as model for neurosecretion
Webb14 apr. 2024 · PC12 cells synthesise and store dopamine and are a suitable model for the study of catecholaminergic neurotoxicity in vitro. Widespread use of PC12 cells is to study the neurotoxic activity of various substances, for example, by assessment of the effect on cell survival, neurite outgrowth, DNA damage or protein expression levels.
WebbLanguage Label Description Also known as; English: PC12. cell line how to set clock on ihomeWebbFor this, commercial immortal neuronal cell lines, which can simulate neurons after differentiation process are available: PC12, SH-SY5Y, bEnd.3, TR-BBB, HBMEC, BV2, etc. … how to set clock on ihome clock radioWebb15 juni 2024 · PC-12 cell line is preferred as model in neurobiology studies because of its neurogenic characteristics (after differentiation) such as neurotransmitters secretion … notdreampcs instagramWebbThis review attempts to touch on the history and application of amperometry at PC12 cells for fundamental investigation into the exocytosis process. PC12 cells have been widely used as a model for neural differentiation and as such they have been used to examine the effects of differentiation on exocytotic release and specifically release at varicosities. how to set clock on insignia microwaveWebb17 okt. 2024 · The rat pheochromocytoma cell line, PC12, has become a major model system to study many aspects of neuronal activity since its development and … how to set clock on hp envy laptopWebbPC12 cells contain a large number of secretory granules for storage of small molecules, processing enzymes, neuropeptides, and peptide hormones. Secretory granule exocytosis in PC12 cells is tightly regulated by calcium and occurs in response to a secretagogue (Bader et al., 2002 ). notdred twitterWebbRESEARCH Electrochemistry, imaging with optical (STED) and mass spectrometry (SIMS, NanoSIMS) methods aimed at understanding the chemistry of single nerve cells, single … notdienstsuche apotheke