The accessible surface area (ASA) or solvent-accessible surface area (SASA) is the surface area of a biomolecule that is accessible to a solvent. Measurement of ASA is usually described in units of square angstroms (a standard unit of measurement in molecular biology). ASA was first described by Lee & Richards in … See more Shrake–Rupley algorithm The Shrake–Rupley algorithm is a numerical method that draws a mesh of points equidistant from each atom of the molecule and uses the number of these points that are … See more Accessible surface area is often used when calculating the transfer free energy required to move a biomolecule from an aqueous solvent to … See more • Implicit solvation • Van der Waals surface • VADAR tool for analyzing peptide and protein structures • Relative accessible surface area See more The ASA is closely related to the concept of the solvent-excluded surface (also known as the Connolly's molecular surface area or simply … See more • Network Science, Part 5: Solvent-Accessible Surfaces • AREAIMOL is a command line tool in the CCP4 Program Suite for calculating ASA. • NACCESS solvent accessible area calculations. See more WebMay 1, 2004 · Accessible surface area (ASA) or solvent accessibility of amino acids in a protein has important implications. Knowledge of surface residues helps in locating potential candidates of active sites. Therefore, a method to quickly see the surface residues in a two dimensional model would help to immediately understand the population of …
ASAView: Database and tool for solvent accessibility …
WebSolvent accessible surface area of a protein molecule is its surface area that is in contact with the solvent in which it resides. It will depend on the three dimensional structure of … WebSep 30, 2024 · This video explains how to calculate the accessible surface area (SASA) or solvent-accessible surface area (SASA) of protein using VMD. SASA is the surface... greenacres property for sale in france
A review of methods available to estimate solvent …
WebJun 5, 2024 · In this article, we explore an alternative to the analytical Gauss-Bonnet approach for computing the solvent-accessible surface area (SASA) and its nuclear … WebJun 1, 2024 · So your SASA_Descriptor Score of 14.15 is telling you that just over 14% of the molecule is exposed to ligand (or that just under 86% is buried in the receptor). Higher scores mean that more of ... WebPISA and Accessible and Buried Surface Area. The 'View' 'Interface' option, using JMol, from the 'Interface Details' page, gives a excellent indication of the meaning of these terms. The non-interfacing atoms which are solvent accessible, are coloured light blue and dark blue for the two molecules respectively. Inaccessible atoms are coloured grey. flower made from ribbon