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Web1 Sep 2007 · J Clin Oncol. 2007 Sep 1;25(25):3991-4008 ... R Carver 1 , Charles L Shapiro, Andrea Ng, Linda Jacobs, Cindy Schwartz, Katherine S Virgo, Karen L Hagerty, Mark R Somerfield, David J Vaughn, ASCO Cancer Survivorship Expert Panel. Affiliation 1 Abramson Cancer Center of the University of Pennsylvania, Philadelphia, PA , USA. PMID ... Web25 May 2024 · 9503 Background: The immunomodulatory receptor TIGIT is a novel inhibitory immune checkpoint present on activated T cells and NK cells in multiple cancers, including NSCLC. In a phase I study (GO30103), co-inhibition of TIGIT and PD-L1 signaling with tira plus atezo in CIT-naïve PD-L1 positive NSCLC potentially improved overall response rates … stephens tn
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