Palbociclib molecular weight
Web4 Approved. Molecular Formula: C24H29N7O2. Molecular Weight: 447.54. ChEMBL Synonyms: PALBOCICLIB PD-0332991. Synonyms From Alternative Forms: PALBOCICLIB ISETHIOLATE PALBOCICLIB ISETHIONATE PD 0332991-0054 PD-03329910054 PD-0332991-0054 PF-0008066573 PF-00080665-73. WebThe main research efforts in this field are currently focused on Palbociclib and ... (everolimus, sirolimus, temsirolimus), the average molecular weight of drugs is 480 with a range of 306 ...
Palbociclib molecular weight
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WebDec 7, 2024 · Palbociclib is a reversible cyclin dependent kinase 4 and 6 ... Cytogenetic, molecular, and flow analyses were normal. Patients were managed expectantly, and when palbociclib was discontinued for breast cancer progression, the macrocytic anemia resolved to baseline Hb and MCV values within 4 months of stopping therapy. WebApr 8, 2024 · CDK 4/6 inhibitors have demonstrated significant improved survival for patients with estrogen receptor (ER) positive breast cancer (BC). However, the ability of these promising agents to inhibit bone metastasis from either ER+ve or triple negative BC (TNBC) remains to be established. We therefore investigated the effects of the CDK 4/6 …
WebThe molecular formula for palbociclib is C 24 H 29 N 7 O 2. The molecular weight is 447.54 daltons. The chemical name is 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8 H)-one, and its structural formula is: Palbociclib is a yellow to orange powder. WebPalbociclib is an orally available cyclin-dependent kinase (CDK) ... What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol? Enter …
WebPalbociclib Cat. No.: HY-50767 CAS No.: 571190-30-2 Molecular Formula: C₂₄H₂₉N₇O₂ Molecular Weight: 447.53 Target: CDK Pathway: Cell Cycle/DNA Damage Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 … WebMolecular Weight. Product Data; Handling; Safety Information; Details; Specifications Purity ≥98% (HPLC) Identity 1H-NMR Appearance Light-yellow or off-yellow powder, beige Properties Solvents ... Palbociclib is a potent and selective inhibitor of CDK4 (IC50=11nM) and CDK6 (IC50=16nM).
WebMolecular Formula: C24H29N7O2: Molecular Weight: 447.53: Category: ... Palbociclib Impurity A is related to the parent compound, Palbocicib (P139900) (also known as compound number PD-0332991), which is an experimental drug for the treatment of breast cancer being developed by Pfizer.
trace danskWebChemical Modulators for studying Palbociclib in the research area. ... Molecular Weight: 447.5 g/mol: Purity >98%: Molecular Formula: C 24 H 29 N 7 O 2: CAS: 571190-30-2: … trace and track j\u0026tWebMolecular Formula. C14H22N4O2. Molecular Weight. 278.35. Size Price Stock Quantity; 100 mg: $229: In stock: ... Palbociclib is the first U.S. Food and Drug Administration-approved cyclin-dependent kinase inhibitor indicated in combination with letrozole for … trace bikeWebApr 28, 2024 · The mice in the control group maintained body weight throughout the treatment, while the mice that received 150 mg·kg −1 palbociclib showed a slight loss in body weight (Fig. S6). To explore the molecular mechanisms underlying the tumor-suppressive effect of palbociclib, the xenografted tumors were subjected to PP5 activity … trace an object njWebMolecular Weight: 447.53 CAS No. : 571190-30-2 4. FIRST AID MEASURES 4.1 Description of first aid measures ... Palbociclib-SDS-MedChemExpress Author: MedChemExpress Subject: Palbociclib-SDS-MedChemExpress Keywords: Palbociclib-SDS-MedChemExpress Created Date: 1/23/2024 6:52:48 PM ... trace adkins even jesusWebN-Nitroso Palbociclib is an impurity present in Palbociclib, ... Molecular Formula: C24H28N8O3. Molecular Weight: 476.53 g/mol. Parent drug: Palbociclib. IUPAC Name: 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)pyrido[2, 3-d]pyrimidin-7(8H)-one. trace a snakeWebJan 3, 2024 · Ibrance capsules for oral administration contain 125 mg, 100 mg, or 75 mg of palbociclib, a kinase inhibitor. The molecular formula for palbociclib is C 24 H 29 N 7 O 2. The molecular weight is 447.54 daltons. trace brazuca vivo