Orbitally shaken bioreactors are widely used for small-scale screening and process optimization. Complex mechanical and electronic parts such as the shaker drive, the power train, and the control unit are integrated in the shaker and, therefore, separated from the reactor vessel. See more The well-defined and homogeneous liquid distribution during shaking is a key benefit of orbitally shaken single-use reactors. Reproducible flow … See more The applicability of orbitally shaken single-use reactors for aerobic bioprocesses highly depends on their potential to deliver a sufficient amount of oxygen to the cells. The first quantitative characterization of the oxygen transfer in … See more The first detailed characterization of the mixing performance in cylindrical orbitally shaken bioreactors with volumes ranging from 2 to 1,500 L was reported by Tissot et al. [29]. A calorimetric method was used to determine mixing … See more WebMar 1, 2024 · Orbitally shaken bioreactors (OSRs) is one of important bioreactors for mammalian cells cultivation in suspension, especially for the screening of valuable …
Analysis of volumetric mass transfer coefficient - Springer
WebSep 1, 2014 · Shaken bioreactors are extensively used in the early stages of bioprocess development, with micrometer plates (24, 48, 96, or 384 wells) being advantageous for … chef yim
Linear damped interfacial wave theory for an orbitally shaken …
Web: Orbitally shaken single-use reactors are promising reactors for upstream processing, because they fulfill three general requirements for single-use equipment. First, the design … WebNov 15, 2010 · In orbitally shaken bioreactors, the container moves with the shaker, inducing liquid motion through contact with the walls. This mixing system is the same regardless of the scale of operation. Thus, similar mixing principles can be expected at different scales. This may explain why the mixing time did not increase with the scale and why the ... WebThe Boekel Scientific Orbital and Reciprocating Shaking Water Bath is designed for a wide range of temperature-controlled shaking protocols, such as Northern and Southern … fleming title company charleston sc