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WebFeb 25, 2024 · Diabetes can cause nerve damage and poor circulation, especially if a person has difficulty managing blood sugar levels. This can lead to foot ulcers, blisters, pain, and foot infections. WebJul 27, 2009 · In people with diabetes, PAD often affects smaller blood vessels below the knee, which makes it less likely to cause pain and other symptoms. In fact, almost 50 percent of people with diabetes who have PAD experience no symptoms at all. This is in part because many people with diabetes have neuropathy and decreased sensation in … Webpainful. weak. You may feel extreme pain in your feet, legs, hands, and arms, even when they are touched lightly. You may also have problems sensing pain or temperature in these parts of your body. If you have peripheral neuropathy, you may feel burning or tingling, like “pins and needles,” in your feet. Symptoms are often worse at night. chinese red sky event