Cisplatin hyponatremia

WebJul 22, 2024 · Cisplatin-induced kidney toxicity is reviewed here. The use of cisplatin in patients with pre-existing kidney dysfunction and the kidney effects of the platinum … WebApr 7, 2024 · Acute overdosage of spironolactone tablets may be manifested by drowsiness, mental confusion, maculopapular or erythematous rash, nausea, vomiting, dizziness, or diarrhea. Rarely, instances of hyponatremia, hyperkalemia, or hepatic coma may occur in patients with severe liver disease, but these are unlikely due to acute overdosage.

Cancer therapy-induced hyponatremia: A case …

WebNov 1, 1997 · Cisplatin is one of the most widely used agents in cancer treatment. Cisplatin regimens can lead to a more or less pronounced hyponatremia in 4 to 10% of cases due to salt wasting with ... WebDec 20, 2024 · Background: Hyponatremia is a common electrolyte abnormality in cancer patients who receive chemotherapy. Among anticancer agents, platinum-based agents are reported to cause chemotherapy-induced hyponatremia. However, the actual incidence and risk factors remain unknown. Results: The reports of 29 trials were analyzed. greek food truck nyc https://whyfilter.com

Tolvaptan for Hyponatremia Induced by Chemotherapy With Doce ... - LWW

WebKeywords: Cisplatin, Dehydration, Hyponatremia, Renal salt wasting, Siadh. Case Presentation: A 63-year-old male presents to the hospital with complaints of one-day history of weakness, dizziness. His outpatient blood work demonstrated a serum sodium level of 124 mEq/L, and a creatinine of 3.1 mg/dL. His medical history was significant for high ... WebAug 18, 2024 · Water losses from brain cells cause neurologic symptoms. Volume expansion and dilutional hyponatremia, without neurologic symptoms, can also be induced when isotonic mannitol is used as a flushing solution during transurethral resection of the prostate or bladder. WebJul 8, 2010 · Cisplatin based therapy for the treatment of solid organ tumors is commonly associated with several renal abnormalities including; *hypokalemia. * hypomagnesemia. … greek food truck rockford il

Hyponatremia in patients with esophageal cancer treated with

Category:Electrolyte disorders with platinum-based chemotherapy: …

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Cisplatin hyponatremia

Cisplatin-Induced Acute Kidney Injury and Renal Salt …

WebMay 22, 2012 · The development of hyponatremia during cisplatin therapy bears special mention. Cisplatin stimulates AVP secretion to cause SIADH, but it can also directly damage renal tubules to interfere with sodium reabsorption, which in rare cases may lead to hyponatremia via salt wasting nephropathy [ 41 ]. WebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head and neck, bladder, ovarian, and testicular malignancies. 1,2 Approximately 20% of all cancer patients are …

Cisplatin hyponatremia

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WebMar 15, 2024 · For patients who are unable to receive cisplatin due to medical frailty or comorbidities, options include a carboplatin-based regimen ( carboplatin plus gemcitabine, or carboplatin, gemcitabine, and paclitaxel) or a non-platinum-based combination (eg, paclitaxel plus gemcitabine) or even monotherapy (eg, gemcitabine). WebNational Center for Biotechnology Information

WebJan 1, 2024 · Hyponatremia in cancer patients can be caused by a number of factors including gastrointestinal losses, cardiac failure, diabetes insipidus, cancer-induced … WebMar 23, 2024 · With a median follow-up of 12 months, 25 patients in the first-line group and 15 patients in the second-line group died of UTUC. For cisplatin-ineligible first-line patients, the median OS was 18.0 months (95% CI 4.1–31.9), the 1-year OS rate was 65.4%, and the median PFS was 5.0 months (95% CI 2.0–8.0; Figure 1A,B).

WebWe report a case of a patient with hyponatremia and excessive urinary excretion of sodium after cisplatin-based chemotherapy. RSWS was diagnosed and the patient was treated … WebApr 6, 2024 · Treatment-related grade 3/4 hyponatremia was reported in 5%–7% of MIBC patients treated with pre-operative ... NAC and prolonged survival. 34-36 It is hypothesized that these mutations may increase the sensitivity of tumor cells to cisplatin-induced DNA damage, thereby enhancing the drug's efficacy in these tumors. 37 The incidence of DDR ...

WebElectrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management. Platinum chemotherapy, particularly cisplatin, is commonly associated …

WebFeb 16, 2024 · Hyponatremia, defined as a plasma sodium concentration lower than 135mmol/L, is the most common electrolyte disorder found in hospitalized patients.1 Its … flow chart in miroWebJul 1, 2008 · Hyponatremia associated with platinum compounds is described more frequently with cisplatin than with carboplatin. 42, 43 The possible underlying pathophysiological mechanisms by which cisplatin induces hyponatremia are SIADH and renal salt wasting. 44 Cisplatin-induced hyponatremia often is combined with … flow chart in minitabWebNov 21, 2024 · Cisplatin probably causes hyponatremia by causing SIADH and through its effect on the kidneys. ( 5 Trusted Source A Review of Drug-induced Hyponatremia Go to source) Painkillers: Opiates,... flow chart in microsoft powerpointWebSep 1, 2024 · Cisplatin for injection has been administered at 20 mg/m 2 intravenously daily for 5 days per cycle. Other doses and combination regimens have been used. ... other electrolyte abnormalities (hypocalcemia, hyponatremia, hypokalemia, and hypophosphatemia), Syndrome of Inappropriate Antidiuretic Hormone Excretion … flow chart in ms officeWebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including acute kidney injury with reduced glomerular filtration, Fanconi syndrome, and renal tubular acidosis, nephrogenic diabetes insipidus and renal salt wasting syndrome. greek food truck njhttp://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf greek food truck st louisWebHyponatremia due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) or gastrointestinal loss of sodium is sometimes seen during chemotherapy. However, … greek food tucson speedway